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. Author manuscript; available in PMC: 2011 Jul 18.
Published in final edited form as: Vaccine. 2009 Dec 23;28(7):1746–1757. doi: 10.1016/j.vaccine.2009.12.016

Fig. 3.

Fig. 3

Proliferation of murine spleen and lymph node cells to L. sigmodontis antigen (LsAg) and anti-CD3/anti-CD28. Shown is the stimulation index (OD of stimulated cells/baseline)*100. Mice were vaccinated with irradiated L. sigmodontis L3s and/or given repeated parasite exposures (RPE) with irradiated larvae for two (open bars) or eight weeks (grey bars). Control groups were vaccinated with media and then given repeated media injections. Significant differences between groups were analyzed by the Kruskal-Wallis test, followed by Dunn’s post-hoc multiple comparisons (*p<0.05). Timepoints listed are duration of RPEs. Shown are results from two independent experiments (2 week timepoint: RPE n=5, Vaccination n=8, Vaccination + RPE n=8; 8 week timepoint: RPE n=4, Vaccination n=7, Vaccination + RPE n=8).