Figure 3.

(A) UV spectrum of oligonucleotide 14, single strand (– – –) and duplex (—). (B) CD spectrum of duplexes containing modified oligonucleotides 12 (- - -), 13 (– – –), and 14 (– - –) and the unmodified NarI sequence (—).

(A) UV spectrum of oligonucleotide 14, single strand (– – –) and duplex (—). (B) CD spectrum of duplexes containing modified oligonucleotides 12 (- - -), 13 (– – –), and 14 (– - –) and the unmodified NarI sequence (—).