Table 1.
Mass Spectral Characterization of the N2-IQ-Modified Oligonucleotides Used in This Study (G = dGuo-N2-IQ)a
| Oligonucleotide | m/z (Da) | |
|---|---|---|
| 12 | 5′-CTC-G1GCGCC-ATC-3′ | 3111A9 |
| 13 | 5′-CTC-GG2CGCC-ATC-3′ | 3776.54 |
| 14 | 5′-CTC-GGCG3CC-ATC-3′ | 3776.26 |
| 15 | 5′-G-GCA-G1GT-GGT-G-3′ | 3647.89 |
The calculated masses for oligonucleotides 12–14 and 15 (M – H) are 3776.58 and 3647.76 Da, respectively.