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. Author manuscript; available in PMC: 2012 Jun 28.
Published in final edited form as: ACS Nano. 2011 Jun 1;5(6):4581–4591. doi: 10.1021/nn200283g

Figure 6.

Figure 6

Effect of MWNCTs on NFκB activation (A), iNOS (B) and Src-family of PTK (C) expression. Degradation of IκBα and translocation of p65 protein into the nucleus are indicators for activation of NFκB signaling pathway. Macrophages were treated with 97.6 μg/mL of MWNCT 1 or 95.9 μg/mL of MWNCT 2 for 24 hrs. The cytoplasm or nuclear extracts were analyzed by western blot for IκBα, p65, iNOS and Src-family of PTK in cytoplasm and p65 in nuclear. For equal protein loading of cytoplasmic extracts, the cytoplasm extracts were analyzed with anti-β-actin antibody and for nuclear extracts with anti-PARP antibody.