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Nuclear N1-ICD misexpression in Dox-treated KR/TC/R26fN1-ICD/WT (POMCN1-ICD) mice at E15.5. Immunofluorescent staining with anti-Notch1 antibody. Red: Notch positive signal. Blue: DAPI nuclear counterstain. Note that Notch1-positive signals are rare in POMCwild-type eye (A,Aa), but abundant in POMCN1-ICD eyelid and corneal stroma (B,Ba,Bb,Bc). Co, cornea; Le, lens; LL, lower eyelid; Re, retina; UL, upper eyelid.
