Figure 4.

Effect of NDGA on TPA induced (a) GSH level, (b) GPx, (c) GR and (d) GST activity in mouse skin from different treatment groups. Values are expressed as means ± SE (n = 6) of GSH/g tissue, GPx and GR activities as nmol NADPH oxidized/min/mg protein, GST activity as nmol CDNB conjugates formed/min/mg protein. Significant differences are indicated by ***P < .001 when compared with control animals (Group I) and # P < .05, ## P < .01 and ### P < .001 and when compared with TPA-treated animals (Group II).