Table 2. Differential expression of genes in the JAK–STAT signaling pathway in MPN patients.

	Gene	Group 1	Group 2	Group 3
1	ACTB	10.9	7.1	(−3.1)
2	SOCS3	7.5	2.2	(−1.7)
3	JAK2	4.4	(2.7)	(2.0)
4	JAK3	4.2	(2.0)	(1.7)
5	FAS	4.1	(2.4)	2.7
6	SPI1	3.9	2.1	(1.6)
7	STAT5B	3.6	(1.5)	(−1.5)
8	IFNGR1	2.7	(1.6)	(1.1)
9	SP1	2.6	(1.9)	(1.3)
10	IRF9	2.6	(1.6)	(−1.1)
11	STUB1	2.4	(1.6)	(1.8)
12	GAPDH	2.3	(−1.2)	2.0
13	JUNB	2.2	(−1.1)	(−1.3)
14	FCGR1A	2.1	(1.3)	−2.2
15	STAT3	1.7	(1.5)	(1.1)
16	SRC	−1.6	(1.1)	(1.3)
17	HMGA1	−1.6	(−1.2)	(−1.4)
18	HPRT1	−1.8	(−1.6)	−1.5
19	IL2RA	−1.9	(−1.6)	−1.8
20	CSF2RB	−1.9	−1.6	−3.5
21	SOCS1	−2.2	−2.0	−3.9
22	IL20	−2.2	(1.0)	(−2.0)
23	TYK2	−2.3	(−1.4)	−2.0
24	SOCS2	−2.3	(−1.4)	(−2.5)
25	EPOR	−2.3	(−1.5)	−2.2
26	YY1	−2.5	−1.7	−2.8
27	STAT1	−2.5	(−1.5)	−2.6
28	SOCS4	−2.5	(−1.6)	(−2.5)
29	MMP3	−2.5	(−1.4)	(−2.8)
30	IL2RG	−2.6	−2.1	−3.4
31	IL4	−2.7	(−1.6)	(−2.8)
32	SOCS5	−2.7	(−1.6)	(−2.8)
33	PTPRC	−2.9	(−1.8)	−3.5
34	JAK1	−2.9	(−1.6)	−2.5
35	USF1	−3.3	−1.7	−2.8
36	OAS1	−3.3	(−1.5)	(−2.3)
37	SLA2	−3.4	(−1.3)	(−1.6)
38	IL6ST	−3.5	(−1.6)	−4.7
39	MYC	−3.6	(−2.1)	−2.1
40	IFNG	−4.1	−2.3	−2.0
41	NR3C1	−4.2	−2.4	−4.3
42	SMAD2	−4.2	(−1.7)	−2.5
43	PPP2R1A	−4.3	−2.5	−3.3
44	IRF1	−4.5	−2.1	−4.5
45	GATA3	−5.6	−2.5	−2.4
46	STAT2	−5.8	−2.2	−3.8
47	IL10RA	−6.4	−2.6	−4.5
48	CSF1R	−8.2	−2.9	−3.6
49	SH2B1	−8.7	−3.4	−5.2
50	RPL13A	−9.1	−3.3	−4.0
51	SIT1	−9.6	−3.0	−4.7
52	STAT4	−11.0	−3.6	−5.3
53	A2M	−11.3	−3.7	−3.8

Selected genes analyzed by JAK–STAT-related PCR array that showed statistically significant (p<0.05) up- or downregulation between the group 1 and the control group are shown. The magnitude of differences for groups 2 and 3 are also shown. Positive and negative numbers indicate up- and downregulation, respectively. Numbers in parentheses indicate a lack of statistical significance (p>0.05) in comparison with the control group.