. 2001 Mar 28;2:4. doi: 10.1186/1471-2350-2-4

Table 3.

Allele and genotype distribution of the Ala(-9)Val SOD2 polymorphic marker in type 1 diabetic patients with and without neuropathy

Group	Allele frequency n (%)		Genotype frequency n (%)

	Ala	Val	Ala/Ala	Ala/Val	Val/Val
Neuropathy (n = 82)	83^a (50.6)	81^b (49.4)	14^c (17.1)	55 (67.0)	13^d (15.9)
No neuropathy (n = 84)	115 (68.5)	53 (31.5)	33 (39.3)	49 (58.3)	2 (2.4)

^a Ala allele frequency was significantly lower in patients with diabetic neuropathy than in subjects without this complication (odds ratio = 0.48, p = 0.00067, p_c = 0.00134). ^b Val allele frequency was significantly higher in patients with diabetic neuropathy than in subjects without this complication (odds ratio = 2.10, p = 0.00067, p_c = 0.00134). ^c Ala/Ala genotype frequency was significantly lower in patients with diabetic neuropathy than in subjects without this complication (odds ratio = 0.34, p = 0.00122, p_c = 0.00366). ^d Val/Val genotype frequency was significantly higher in patients with diabetic neuropathy tha in subjects without this complication (odds ratio = 5.10, p = 0.00219, p_c = 0.00657).