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Percentage of Ski+/− and Ski−/− MEF containing Micronuclei and Other Chromosome segregation abnormalities
| MEF Genotypea | % of cells with Micronuclei | % of cells with Other Segregation Defectsb |
|---|---|---|
| Ski+/− | 30±6 | 13±1 |
| Ski−/− | 41.5±8* | 65±3* |
Five-hundred cells of each cell type were examined. N=3 for each genotype
Include Chromosome/chromatin bridges and lagging chromosomes
p<0.005 compared to Ski+/− MEF (Chi-Square Test).
