Table 3.
Ski Expressiona | Total no. of cell counted | No. of cells with cell death characteristicsb | % of cells with cell death characteristics |
---|---|---|---|
NO | 348 | 4 | 1.1 |
YES | 409 | 48 | 10.5* |
Abbreviation: Dox, Doxycycline
Ski expression was induced by Doxycycline withdraw in Ski−/− MEF.
Gigantic cells with fragmented non-condensed nuclei (Mitotic catastrophe, as shown in Supplementary Figure 1) and cells with highly condensed and/or fragmented DNA (Apoptosis, as in Figure 6).
p<0.001 compared to Ski−/− MEF not expressing Ski (Fisher’s exact Test).