Table 3.

Quantification of Cell Death in Ski expressing (Dox−) and not expressing (Dox+) MEF

Ski Expressiona	Total no. of cell counted	No. of cells with cell death characteristicsb	% of cells with cell death characteristics
NO	348	4	1.1
YES	409	48	10.5*

Abbreviation: Dox, Doxycycline

^aSki expression was induced by Doxycycline withdraw in Ski−/− MEF.

^bGigantic cells with fragmented non-condensed nuclei (Mitotic catastrophe, as shown in Supplementary Figure 1) and cells with highly condensed and/or fragmented DNA (Apoptosis, as in Figure 6).

^*p<0.001 compared to Ski−/− MEF not expressing Ski (Fisher’s exact Test).