Table 1.
Maternal demographics and methadone dosing data (n=19).
| Subject | Age | Race | # cigarettes/day | EGAA (weeks) | Days in study | Initial dose (mg) | Dose at delivery (mg) | Mean daily dose (mg/day) | Mean 3rd trimester daily dose (mg/day) | Cumulative dose (mg) | Cumulative 3rd trimester dose (mg) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 32 | AA | 20 | 25 | 53 | 50 | 30 | 29.6 | 30.0 | 1,715 | 1,200 |
| 2 | 23 | O | 10 | 28 | 76 | 20 | 60 | 37.9 | 37.9 | 3,070 | 3,070 |
| 3 | 34 | AA | 10 | 27 | 89 | 60 | 85 | 69.9 | 69.9 | 3,215 | 3,215 |
| 4 | 35 | C | 0 | 29 | 65 | 60 | 80 | 67.5 | 67.5 | 4,590 | 4,590 |
| 5 | 33 | AA | 8 | 25 | 104 | 30 | 45 | 44.7 | 45.0 | 4,695 | 4,230 |
| 6 | 32 | AA | 20 | 14 | 102 | 30 | 75 | 71.5 | 75.0 | 6,010 | 1,800 |
| 7 | 19 | C | 20 | 20 | 121 | 30 | 65 | 63.1 | 64.5 | 6,565 | 6,195 |
| 8 | 31 | AA | 8 | 24 | 81 | 50 | 90 | 79.2 | 86.8 | 6,815 | 5,205 |
| 9 | 21 | C | 40 | 20 | 113 | 40 | 70 | 70.0 | 73.7 | 7,980 | 4,495 |
| 10 | 30 | AA | 0 | 23 | 124 | 50 | 70 | 65.5 | 68.6 | 8,320 | 6,650 |
| 11 | 25 | AA | 14 | 22 | 102 | 40 | 95 | 80.5 | 85.7 | 8,450 | 5,910 |
| 12 | 19 | AA | 10 | 17 | 176 | 30 | 60 | 59.5 | 60.0 | 8,980 | 4,800 |
| 13 | 34 | AA | 3 | 24 | 127 | 50 | 80 | 70.5 | 74.7 | 9,300 | 7,990 |
| 14 | 31 | AA | 0 | 10 | 132 | 30 | 90 | 73.6 | 89.7 | 9,795 | 3,945 |
| 15 | 34 | AA | 10 | 23 | 111 | 90 | 110 | 100.4 | 102.5 | 11,245 | 8,100 |
| 16 | 25 | B | 20 | 20 | 141 | 40 | 70 | 81.3 | 86.1 | 11,540 | 7,405 |
| 17 | 26 | C | 20 | 17 | 139 | 40 | 100 | 86.5 | 97.0 | 12,110 | 6,690 |
| 18 | 30 | AA | 0 | 16 | 176 | 40 | 85 | 74.1 | 81.2 | 12,964 | 8,040 |
| 19 | 32 | AA | 0 | 11 | 200 | 30 | 70 | 66.3 | 70.0 | 13,335 | 6,160 |
| Mean | 28.7 | - | 11.2 | 20.8 | 117.5 | 42.6 | 75.3 | 68.0 | 71.9 | 7,931.3 | 5,246.8 |
| SD | 5.3 | - | 10.4 | 5.5 | 38.4 | 15.9 | 19.0 | 16.6 | 19.0 | 3,462.7 | 2,046.7 |
| Median | 31.0 | - | 10.0 | 22.0 | 113.0 | 40.0 | 75.0 | 70.0 | 73.7 | 8,320.0 | 5,205.00 |