Table 2.

Neonatal outcome measures for the 19 in utero methadone-exposed infants. Normal estimated gestational age at birth (EGAB) is ≥ 37 weeks, normal weight≥2,500 g, normal head circumference≥ 32 cm and normal length≥ 45 cm. Bolded text indicate below normal parameters.

Subject	Mother smoker	EGAB (weeks)	Weight (g)	Head circumference (cm)	Length (cm)	1 min Apgar Score	5 min Apgar Score	Time to NAS onset (h)	Peak NAS score	Time-to-peak NAS score (h)	NAS duration (h)	%NAS Scores>4
1	YES	32.0	2,080	32	45.0	9	9	6.3	10	119.6	113.3	66.7
2	YES	34.0	2,745	33	48.0	8	8	-*	4	16.5	-*	-*
3	YES	32.0	2,995	33	49.0	8	9	3.5	14	89.5	341.0	89.7
4	NO	37.0	3,110	34	50.0	7	9	30.0	15	75.8	58.5	12.7
5	YES	40.4	4,370	36	51.0	8	9	12.7	6	30.7	45.0	28.6
6	YES	30.4	1,505	26	41.0	9	9	13.0	10	13.0	96.0	31.6
7	YES	40.0	4,025	35.5	49.0	9	9	26.0	9	69.7	59.5	47.8
8	YES	36.0	3,650	33	52.5	9	9	28.5	19	194.0	289.5	66.7
9	YES	35.0	2,740	32	50.0	8	8	54.0	6	54.0	22.0	18.5
10	NO	39.0	3,760	34.5	51.0	9	9	23.5	11	30.5	86.7	55.8
11	YES	31.0	2,850	33	47.0	8	9	60.7	8	80.7	154.5	51.4
12	YES	38.3	2,385	30.5	43.5	8	9	19.4	8	61.1	61.7	69.6
13	YES	40.0	2,675	34	48.0	8	9	127.8	7	166.3	49.0	6.3
14	NO	33.3	2,125	30	43.5	8	9	40.4	8	40.4	12.0	25.0
15	YES	38.0	2,515	30	48.0	9	9	23.2	6	23.2	48.0	13.6
16	YES	39.3	2,865	32	46.0	8	8	19.0	7	30.0	556.0	84.5
17	YES	35.0	3,180	34	52.0	7	9	13.3	14	77.3	320.5	90.1
18	NO	41.0	3,140	34	51.0	8	9	16.0	8	16.0	25.0	66.7
19	NO	38.9	4,810	36	52.0	9	9	38.2	11	60.0	22.2	22.2
Mean	-	36.3	3,027.6	32.8	48.3	8.3	8.8	30.9	9.5	65.7	131.1	47.1
SD	-	3.4	816.3	2.4	3.3	0.7	0.4	28.6	3.8	49.8	148.5	28.0
Median	-	37.0	2,865.0	33.0	49.0	8.0	9.0	23.4	8.0	60.0	60.6	49.6

NAS: neonatal abstinence syndrom

^*No data on time to NAS onset, NAS duration and %NAS scores >4 for participant 16.