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. Author manuscript; available in PMC: 2012 Aug 15.
Published in final edited form as: Neuroimage. 2011 May 3;57(4):1458–1465. doi: 10.1016/j.neuroimage.2011.04.052

Figure 1.

Figure 1

Top row, left (A–C) shows (A) representative DWIs from the 21-direction MR data. The difference in contrast between the two images is the result of the differing diffusion gradient directions employed. From these data, the tensor map (B) is obtained and the image pixels with predominantly in-plane structure (dark red) are mapped (C). Bottom row, left (D–F) shows (D) left: the coregistered Black Gold II stained histology (otherwise unprocessed), right: the histology after color inversion (E) the binary map of structural components visible in the histology after processing and down sampling to a resolution matching the MRM. The micro surface-coil’s approximate FOV is indicated (red oval) (F) The portion of the histological binary map which corresponds to the coil’s FOV. The two coregistered maps thus obtained (C and F) form the basis for calculation of the fraction of tensor map pixels supported by the histology. The gray area around the histology map in (F) is to illustrate the masking employed so that only histology within the coil FOV is included in the final steps of the analysis. In this particular experiment which corresponds to the tissue sample from figure 4 (far left column, rotated 90 degrees), the degree of correspondence is 0.82 which was the lowest of the three values calculated in the current study.