Table 1.
Intermediate outcomes measured at recruitment of cohort in 1975-7. Probability measures are odds ratios for dichotomous outcomes (estimated with logistic regression models) and mean differences for continuous outcomes (estimated with linear regression models), both with 95% confidence intervals. All estimates adjusted for birth cohort
|
Age at siege (years)
|
Tests for heterogeneity
|
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|---|---|---|---|---|---|---|---|
| Dependent variable | Any age | ≤ 8 | 9-15 | 16-26 | Not in siege (reference) | LR*P value | Wald†P value |
| Overweight (BMI ≥25) | 0.89 (0.78 to 1.02) | 0.90 (0.64 to 1.27) | 0.83 (0.69 to 1.00) | 0.97 (0.78 to 1.20) | 1.00 | 0.25 | 0.29 |
| Obesity (BMI ≥30) | 1.00 (0.82 to 1.22) | 0.95 (0.52 to 1.75) | 1.13 (0.85 to 1.50) | 0.90 (0.68 to 1.21) | 1.00 | 0.79 | 0.31 |
| Difference in BMI | −0.16 (−0.38 to 0.07) | −0.31 (−0.90 to 0.27) | −0.19 (−0.50 to 0.13) | −0.07 (−0.43 to 0.28) | 0.00 | 0.51 | 0.86 |
| Height ≤163 cm | 0.91 (0.75 to 1.10) | 0.90 (0.54 to 1.49) | 0.91 (0.70 to 1.19) | 0.92 (0.68 to 1.24) | 1.00 | 0.82 | 0.99 |
| Difference in height (cm) | 0.12 (−0.29 to 0.54) | 0.42 (−0.66 to 1.50) | −0.20 (−0.78 to 0.38) | 0.44 (−0.22 to 1.09) | 0.00 | 0.41 | 0.11 |
| Skinfold thickness ≥15.3 mm | 1.14 (0.95 to 1.37) | 1.17 (0.70 to 1.96) | 1.15 (0.89 to 1.50) | 1.12 (0.85 to 1.48) | 1.00 | 0.59 | 0.97 |
| Difference in skinfold thickness (mm) | 0.15 (−0.16 to 0.47) | −0.09 (−0.90 to 0.72) | 0.17 (−0.26 to 0.60) | 0.20 (−0.29 to 0.70) | 0.00 | 0.72 | 0.84 |
| LDL/HDL cholesterol ≥4 | 1.03 (0.86 to 1.23) | 0.88 (0.54 to 1.44) | 1.09 (0.84 to 1.39) | 1.01 (0.77 to 1.33) | 1.00 | 0.84 | 0.49 |
| Difference in LDL/HDL cholesterol | −0.02 (−0.10 to 0.06) | −0.01 (−0.22 to 0.19) | −0.01 (−0.12 to 0.10) | −0.04 (−0.16 to 0.08) | 0.00 | 0.93 | 0.78 |
| Systolic BP ≥160 mm Hg | 1.30 (1.10 to 1.54) | 0.64 (0.33 to 1.25) | 1.56 (1.21 to 2.02) | 1.22 (0.97 to 1.53) | 1.00 | 0.0006 | 0.03 |
| Difference in systolic BP (mm Hg) | 1.88 (0.44 to 3.32) | −2.02 (−5.75 to 1.71) | 3.26 (1.27 to 5.26) | 1.32 (−0.95 to 3.59) | 0.00 | 0.003 | 0.03 |
| Diastolic BP ≥95 mm Hg | 1.18 (1.03 to 1.35) | 0.92 (0.63 to 1.35) | 1.20 (0.99 to 1.45) | 1.23 (0.99 to 1.52) | 1.00 | 0.07 | 0.71 |
| Difference in diastolic BP (mm Hg) | 0.87 (0.07 to 1.67) | −1.35 (−3.41 to 1.32) | 1.33 (0.23 to 2.44) | 0.95 (−0.31 to 2.20) | 0.00 | 0.02 | 0.14 |
| Coronary heart disease‡ | 1.07 (0.88 to 1.29) | 0.49 (0.22 to 1.09) | 1.19 (0.90 to 1.58) | 1.07 (0.82 to 1.39) | 1.00 | 0.12 | 0.21 |
BMI=body mass index.
LDL/HDL=low density lipoprotein/high density lipoprotein.
Likelihood ratio test that outcome was equally likely in each category (≤8, 9-15, 16-26, not in siege). Under the null hypothesis the test statistic has χ2 distribution with 3 df.
Wald test that siege effect was same for those aged 9-15 at siege as for those aged ≤8 or 16-26. Under the null hypothesis the test statistic has χ2 distribution with 1 df.
Presence according to Rose questionnaire.