Table 5.

Results of fertility studies

Antigen	Immunization route/(times)	Number of fertile mice (%)	Mean # embryos/mouse
rMOMP	i.vag./col. (4X)	6/14 (43)a	2.0±2.9b
rMOMP	i.n./s.l. (4X)	11/15 (73)a	4.9±4.0 b,c
rMOMP	i.m./s.c. (4X)	14/21 (67)a	3.7±3.9b,c
rMOMP	i.vag./col. (2X) + i.m./s.c. (2X)	17/21 (81)a,d	5.0±3.3b,c
rMOMP	i.n./s.l. (2X) + i.m./s.c. (2X)	21/21 (100)d,e	6.0±3.0c,f,g
MoPn	i.n. (1X)	21/21 (100)e	4.8±2.9b
Ng-rPorB	i.m./s.c. (4X)	8/16 (50)a	3.0±3.8b,c
---	Fertility control	23/23 (100)d,e	7.2±3.0f

^aP<0.05 by the Fisher’s Exact test compared to the fertility control group.

^bP<0.05 by the Student’s t test compared to the fertility control group.

^cP>0.05 by the Student’s t test compared to the MoPn immunization group.

^dP>0.05 by the Fisher’s Exact test compared to the MoPn immunization group.

^eP<0.05 by the Fisher’s Exact test compared to the Ng-rPorB immunization group.

^fP<0.05 by the Student’s t test compared to the Ng-rPorB immunization group.

^gP>0.05 by the Student’s t test compared to the fertility control group.