Skip to main content
. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: J Neuroimmunol. 2011 May 14;236(1-2):17–26. doi: 10.1016/j.jneuroim.2011.04.008

Figure 4. CCR4 deficiency does not affect the peripheral T helper cell response.

Figure 4

Immunized WT and CCR4−/− mice were killed at onset based on WT clinical disease. Peripheral Th1 and Th17 responses were evaluated by intracellular flow cytometric analysis. (A) Representative flow dot plots displaying IFNγ- and IL-17-producing cells in peripheral lymphoid organs of WT and CCR4−/− mice. The dot plots are derived from a combined forward versus side-scatter and CD45+CD4+ gate. (B) The mean percentage of CD4+ IFNγ- and IL-17-producing cells (±SD) was calculated, and indicates no statistical difference in Th1 or Th17 percentages between groups. Data representative of two separate experiments, n=3.