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Effect of globular adiponectin on the production of interleukin (IL)-6 and IL-8 in THP-1 macrophages. THP-1 macrophages were cultured for 24 hours in the presence of murine myeloma cell-derived globular adiponectin (M-gAd) or lipopolysaccharide (LPS). The levels of IL-6 (A) and IL-8 (B) in culture supernatants were assayed by enzyme-linked immunosorbent. a)Significantly different from untreated cells (P<0.05).
