Fig. 1.

a–c Variability of bilirubin measurements. Measured versus weighed-in bilirubin concentrations (17.1 μmol/L = 1 mg/dL bilirubin) in manufactured samples with albumin concentrations of 0, 10, and 20 g/L, respectively. The median of measured bilirubin concentration is marked by the horizontal line in the central box. The boxes are limited by the 25th and 75th percentile. The whiskers represent minimum and maximum measured bilirubin concentrations. Outliers (white circle) are depicted separately. Coefficients of variations (CV) are shown in Fig. 1b and c as well as the difference between the minimal and maximal measured bilirubin concentration, which is expressed as percentage of the weighed-in bilirubin concentration