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. Author manuscript; available in PMC: 2012 Jul 22.
Published in final edited form as: J Mol Biol. 2011 Jul 22;410(4):716–725. doi: 10.1016/j.jmb.2011.04.069

FIGURE 2. Spry2 mutants used in this study.

FIGURE 2

The location of the PLCγ-binding determinant Y55 and its flanking region in the Spry2 N-terminal domain (NTD) and the PI(4,5)P2-binding determinant R252 in the C-terminal domain (CTD) are indicated. The filled box represents the most conserved region in the otherwise highly divergent NTD.