Figure 5.
Measurement of cytokine production in WT and CD68TGF-βDNRII mice during colitis resolution. (A) Colon tissue lysates from WT and CD68TGF-βDNRII mice were obtained at day 14 following 2% DSS were evaluated by the mouse Proteome Prolifer Array™ (n=3) Data show the mean± SE fold-difference in CD68TGF-βDNRII expression compared to WT. (B) Levels of IL-10 produced in the colon tissue and (C) serum from WT and CD68TGF-βDNRII mice prior to and following 2% DSS administration as determined by ELISA. (n= 6-8) Closed circles (WT) and filled circles (transgenic) that represent mean ± SE are shown. Experiments repeated twice. *=p<0.05, **=p<0.01 as determined by Student t test.