Table 3. Univariate survival analysis of prognostic variables for DSS in endometrioid endometrial cancer patients.
N=139 | ||||
---|---|---|---|---|
Variable | Median | Survival | HR (95% CI) | p |
Age (per yr) | NR | NR | 1.05 (1.02-1.09) | 0.002 |
Stage* | NR | NR | 2.67 (1.21-5.87) | 0.01 |
FIGO grade* | NR | 25 | 4.44 (2.11-9.35) | 0.001 |
Depth of invasion > ½* | NR | NR | 3.18 (1.49-6.78) | 0.003 |
Positive nodes | NR | NR | 0.7 (0.27-1.81) | 0.4 |
High ER | 93 | NR | 0.22 (0.09-0.56) | 0.001 |
High PR | 93 | NR | 0.27 (0.12-0.63) | 0.002 |
High Ki-67 | NR | 93 | 4.19 (1.78-9.86) | 0.001 |
High EphA2 | NR | NR | 4.66 (1.87-11.59) | <0.001 |
For the clinical variables, the groups are sub-classified as low and high as follows: Stage: low (I/II) and high (III/IV); FIGO grade: low (1 or 2) and high (3); Histology: low (endometrioid) and high (non-endometrioid); Depth of invasion: low (≤ ½ myometrial thickness) and high (> ½ myometrial thickness). The same criteria for low and high expression of immunohistochemical variables were used as in Table 2. NR = not reached