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. 2011 May 23;29(19):2628–2634. doi: 10.1200/JCO.2010.32.1877

Table 1.

Patient Characteristics by Tumor Size

Characteristic T1 (n = 834)
T2 (n = 768)
T3/4 (n = 109)
P
No. % No. % No. %
Age, years
    Median 49 48 46
    ≤ 50 467 56.0 461 60.0 73 67.0
    > 50 367 44.0 307 40.0 36 33.0 .047
Lymph nodes
    N0 553 67.4 341 44.8 26 25.0
    N1 201 24.5 280 36.8 29 27.9
    N2 39 4.8 89 11.7 22 21.2
    N3 27 3.3 51 6.7 27 26.0 < .0001
Lymphovascular space invasion
    Negative 631 76.2 484 63.5 45 42.1
    Positive 197 23.8 278 36.5 62 57.9 < .0001
Grade
    1 or 2 93 11.6 65 8.9 12 11.5
    3 708 88.4 664 91.1 92 88.5 .21
Histology
    Ductal 780 93.5 685 89.2 90 82.6
    Other 54 6.5 83 10.8 19 17.4 < .0001
Adjuvant radiation
    No 290 34.8 304 39.6 29 26.6
    Yes 544 65.2 464 60.4 80 73.4 .012
Adjuvant chemotherapy
    Anthracycline based 371 44.5 281 36.6 30 27.5
    Taxane based 31 3.7 37 4.8 3 2.8
    Anthracycline/taxane based 325 39.0 378 49.2 60 55.0
    Nonanthracycline/taxane based 107 12.8 72 9.4 16 14.7 < .0001
Metastatic sites
    Visceral 147 64.2 200 57.1 40 62.5
    Bone only 36 15.7 58 16.6 8 12.5
    Other 46 20.1 92 26.3 16 25.0 .40
No. of metastasis
    1 125 54.6 190 54.3 38 59.4
    2 55 24.0 84 24.0 13 20.3
    3+ 49 21.4 76 21.7 13 20.3 .96