Table 1.
Baseline Patient Characteristics by Beta-Blocker Intake
Characteristic | No Beta Blockers(n = 1,311) |
Beta Blockers (n = 102) |
P | ||
---|---|---|---|---|---|
No. | % | No. | % | ||
Age, years | |||||
Median | 49.0 | 57.0 | |||
Mean | 49.1 | 56.6 | < .001* | ||
< 50 | 694 | 52.9 | 28 | 27.5 | |
≥ 50 | 617 | 47.1 | 74 | 72.5 | < .001 |
Menopausal status | |||||
Pre | 655 | 50.0 | 20 | 19.8 | |
Post | 654 | 50.0 | 81 | 80.2 | < .001 |
Body mass index, kg/m2 | |||||
Median | 27 | 31.4 | |||
< 25 | 452 | 35.6 | 16 | 16.3 | |
25-29 | 413 | 32.5 | 28 | 28.6 | |
30+ | 406 | 31.9 | 54 | 55.1 | < .001 |
Race | |||||
White/other | 1,128 | 86.0 | 83 | 81.4 | |
Black | 183 | 14.0 | 19 | 18.6 | .20 |
Clinical stage | |||||
I | 54 | 4.1 | 3 | 2.9 | |
II | 706 | 54.1 | 60 | 58.8 | |
III | 546 | 41.8 | 39 | 38.2 | .60 |
Nuclear grade | |||||
I | 49 | 3.8 | 1 | 1.0 | |
II | 413 | 32.4 | 37 | 37.4 | |
III | 812 | 63.7 | 61 | 61.6 | .25 |
LVI | |||||
Negative | 861 | 68.0 | 74 | 76.3 | |
Positive | 405 | 32.0 | 23 | 23.7 | .09 |
Hormone receptor status | |||||
Negative | 470 | 35.9 | 35 | 34.3 | |
Positive | 841 | 64.1 | 67 | 65.7 | .76 |
HER2 status | |||||
Negative | 1,062 | 82.1 | 83 | 81.4 | |
Positive | 232 | 17.9 | 19 | 18.6 | .86 |
Triple-negative tumor | |||||
No | 946 | 73.1 | 73 | 71.6 | |
Yes | 348 | 26.9 | 29 | 28.4 | .74 |
Diabetes | |||||
No | 1,240 | 94.6 | 96 | 94.1 | |
Yes | 71 | 5.4 | 6 | 5.9 | .87 |
Insulin use among diabetics | |||||
No | 46 | 64.8 | 6 | 100.0 | |
Yes | 25 | 35.2 | 0 | 0.0 | .17† |
Hypertension | |||||
No | 1,054 | 80.4 | 4 | 3.9 | |
Yes | 257 | 19.6 | 98 | 96.1 | < .001 |
ACEIs/ARBs | |||||
No | 1,211 | 92.4 | 62 | 60.8 | |
Yes | 100 | 7.6 | 40 | 39.2 | < .001 |
Bisphosphonates | |||||
No | 1,276 | 97.3 | 99 | 97.1 | |
Yes | 35 | 2.7 | 3 | 2.9 | .87 |
Metformin use | |||||
No | 1,281 | 97.7 | 98 | 96.1 | |
Yes | 30 | 2.3 | 4 | 3.9 | .30 |
Abbreviations: LVI, lymphovascular invasion; HER2, human epidermal growth factor receptor 2; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker.
Two samplet-test.
Fisher's exact test.