Table 1.
Characteristic | Id Vaccine (n = 76) |
Control (n = 41) |
P* | ||
---|---|---|---|---|---|
No. | % | No. | % | ||
Age at enrollment, years | .146 | ||||
Mean | 49.7 | 51.7 | |||
SD | 9.7 | 9.1 | |||
Male sex | 39 | 51.3 | 28 | 68.3 | .083 |
White race | 67 | 88.2 | 38 | 92.7 | .537 |
ECOG performance status | .222 | ||||
0 | 64 | 84.2 | 30 | 73.2 | |
1 | 12 | 15.8 | 11 | 26.8 | |
Histology | .845 | ||||
FL, grade 1 | 34 | 44.7 | 17 | 41.5 | |
FL, grade 2 | 42 | 55.3 | 24 | 58.5 | |
IgM isotype | 35 | 46.1 | 25 | 61.0 | |
IgG isotype | 40 | 52.6 | 15 | 36.6 | |
IgM/IgG isotype | 1 | 1.3 | 1 | 2.4 | |
Stage | .263 | ||||
II | 2 | 2.6 | 1† | 2.4 | |
III | 29 | 38.2 | 10‡ | 24.4 | |
IV | 45 | 59.2 | 30§ | 73.2 | |
International Prognostic Index | 1.000 | ||||
Low or low intermediate (0-2) | 69 | 90.8 | 37 | 90.2 | |
High intermediate or high (3-5) | 7 | 9.2 | 4 | 9.8 | |
≤ Eight induction chemotherapy cycles | 38 | 50.0 | 22 | 53.7 | .846 |
Abbreviations: ECOG, Eastern Cooperative Oncology Group; FL, follicular lymphoma; Id, hybridoma-derived autologous tumor Ig idiotype; Ig, immunoglobulin; SD, standard deviation.
Comparisons between age groups were performed with nonparametric t-tests using normal approximation (two-sided Wilcoxon test). Comparisons between groups for remaining variables were performed using two-sided Fisher exact test.
P = 1.000 for comparison for stage II representation between two arms.
P = .154 for comparison for stage III representation between two arms.
P = .160 for comparison for stage IV representation between two arms.