Table 2.
Number of subjects per group, age, individual neurobehavioural score, complex NeuroScale score and p-tau181 levels in the longitudinal study
| Longitudinal study | MNI, mean ± SD (range) | SNI, mean ± SD (range) | P level |
|---|---|---|---|
| n | 8 | 8 | |
| Age (days) | 186 | 223.3 ± 11 (206–232) | |
| NeuroScale (score) | 12.8 ± 5.38 (7.8–21.1) | 45 ± 0 (45–45) | <0.05 |
| Beam walking 3 × 3 cm (score) | 2 ± 0.75 (1–3) | 10 ± 0 (10–10) | <0.05 |
| Beam walking 4 × 2 cm (score) | 2 ± 2 (0–5) | 10 ± 0 (10–10) | <0.05 |
| Beam walking 3.5 cm (score) | 3.7 ± 2.65 (0–7) | 10 ± 0 (10–10) | <0.05 |
| Hind limb reflex (score) | 2 ± 0.48 (1.33–3) | 3 ± 0 (3–3) | <0.05 |
| Prehensile traction (score) | 3.1 ± 0.99 (2–4) | 5 ± 0 (5–5) | <0.05 |
| Neurological response (score) | 0 | 7 ± 0 (7–7) | <0.05 |
| P-tau181 (pg/ml) | 62.3 ± 12.38 (50.95–83.41) | 140.8 ± 26.98 (119.7–203.5) | <0.01 |
MNI mild neurobehavioural impairment, SNI severe neurobehavioural impairment