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. 2011 Jul 13;3:257–266. doi: 10.2147/CMR.S12713

Table 3.

Targeted therapies in metastatic gastric cancer: current results

Phase n Regimen RR (%) PFS (m) OS (m)
Bang et al37 III 298/296 Tr-C-5-FU/C-5FU 47/35 (P = 0.0017) 6.7/5.5 (P = 0.0002) 13.8/11.1 (P = 0.0046)
Kang et al38 III 387/387 B-C-5-FU/C-5FU 38/29.5 (P = 0.0121) 6.7/5.3 (P = 0.0037) 12.1/10.1 (NS)
El-Rayes et al39 II 38 B-O-D 42 6.6 11.1
Sun et al40 II 44 Sor-C-D 41 5.8 13.5

Abbreviations: n, number of patients; RR, response rate; TTF, time to treatment failure; PFS, progression free survival; OS, overall survival; Tr, trastuzumab; C, cisplatin; 5-FU, 5-fluorouracil; B, bevacizumab; O, oxaliplatin; D, docetaxel, Sor, sorafenib.