Table 3.
Predictors of weight loss and maintenance in patients treated with orlistat
| Author, year | Predictors | |
|---|---|---|
| Demographic and anthropometric factors | Elfhag et al35 | PPWL: male gender |
| Psychological factors and eating behaviors | Elfhag et al35 | PPWL: high levels of order and deliberation (conscientiousness). High levels of self-discipline and conscientiousness ntPWL: high levels of eating restraint, neuroticism, anxiety, and depression |
| Initial weight loss in the lead-in period and under treatment | Rissanen et al26 | PPWL: Weight loss ≥2.5 kg during 4 weeks lead-in period; weight loss ≥5% body weight after 12 weeks treatment; ≥10% body weight after 6 months |
| Toplak et al38 | PPWL: ≥5% weight loss at 3 and 6 months | |
| Associated medical, dietetic, and environmental factors | Malone and Alger-Mayer40 | ntPWL: pharmacist’s support |
| Toplak et al38 | ntPWL: 500 kc/day diet vs 1000 kcal/day diet | |
| Ullrich et al31 | PPWL: low fat and carbohydrate intake |
Abbreviations: NPWL, negative predictor of weight loss; NPWM, negative predictor of weight maintenance; ntPWL, not predictor of weight loss; ntPWM, not predictor of weight maintenance; PPWL, positive predictor of weight loss; PPWM, positive predictor of weight maintenance.