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SimpleSTEP™ or ExtraSTEP algorithm46
| Efficacy | Period 1 | Period 2 | Period 3 | Period 1 | Period 2 | Period 3 |
|---|---|---|---|---|---|---|
| SimpleSTEP ExtraSTEP | ||||||
| A1C (%) | 8.2 | 7.7 | 7.6 | 8.5 | 7.9 | 7.7 |
| FPG (mmol/L) | 8.2 | 7.6 | 7.6 | 8.0 | 7.6 | 7.4 |
| Hypoglycemia (episodes/yr) | ||||||
| Requiring assistance | 0 | 0 | 0.14 | 0.03 | 0 | 0 |
| No assistance PG < 3.1 mmol/L | 3.5 | 6.1 | 8.8 | 3.3 | 5.5 | 9.3 |
| Weight change at end of trial (kg) | 2.7 | 2.0 |
Abbreviations: A1C, glycosylated hemoglobin; FPG, fasting plasma glucose; PG, plasma glucose.
