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. Author manuscript; available in PMC: 2012 Jul 19.
Published in final edited form as: Biochemistry. 2011 Jun 24;50(28):6208–6216. doi: 10.1021/bi200508f

Figure 9.

Figure 9

Pymol structural alignment of Fe65 PID1 (pink) (PDB accession code 3D8D, (26)) with IRS PID (cyan) bound to the IL-4 receptor NPXY motif (green) (PDB accession code 1IRS, (41)). The phosphotyrosine is colored according to the atoms, the conserved arginines in Fe65 PID1 are red and in IRS PID are blue. Fe65 PID1 R451 and R470 align with the phosphate coordinating arginines of IRS (R212, R227) as shown in the sequence alignment presented with the same color scheme. The alignment was adapted from reference 26.