Table 1.
Demographic, substance use, and morphometry measures by marijuana use group and gender
| Female Controls (n = 11) | Male Controls (n = 36) | Female Users (n = 8) | Male Users (n = 27) | |
|---|---|---|---|---|
| Ethnicity (% Caucasian) | 36% | 40% | 25% | 48% |
| Family history of SUD (% positive) | 9% | 17% | 57% | 26% |
| Cannabis abuse/dependence (% positive) | 0% | 0% | 50% | 81% |
|
|
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| M ± SD | M ± SD | M ± SD | M ± SD | |
|
| ||||
| Age | 17.85 ± 0.73 | 17.65 ± 0.90 | 18.15 ± 0.86 | 17.92 ± 0.91 |
| Hollingshead Index | 26.73 ± 15.56 | 33.22 ± 16.92 | 30.25 ± 13.35 | 25.37 ± 14.25 |
| Vocabulary T-score | 58.82 ± 9.91 | 59.89 ± 8.76 | 58.63 ± 8.35 | 57.70 ± 8.98 |
| Reading standard score | 109.64 ± 5.63 | 110.06 ± 7.49 | 106.38 ± 9.09 | 106.74 ± 8.55 |
| Internalizing composite z-scorea | −0.43 ± 0.58 | −0.47± 0.69 | 0.51 ± 1.25 | −0.33 ± 0.50 |
| Lifetime marijuana use episodesa | 0.36 ± 0.81 | 1.58 ± 2.56 | 397.00 ± 243.03 | 460.07 ± 391.36 |
| Lifetime alcohol use episodesa | 26.60 ± 61.24 | 21.03 ± 27.53 | 239.38 ± 211.15 | 185.70 ± 138.93 |
| Lifetime other drugs use episodesa | 0.18 ± 0.60 | 0.47 ± 2.20 | 8.13 ± 6.10 | 4.48 ± 7.11 |
| Fagerström Test for Nicotine Dependencea | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.30 ± 0.78 |
| Intracranial volume (cc)b | 1,512.61 ± 160.00 | 1,616.23 ± 131.51 | 1,472.83 ± 82.22 | 1,617.80 ± 123.75 |
| Right amygdala (cc) b | 2.03 ± 0.19 | 2.38 ± 0.33 | 2.20 ± 0.29 | 2.30 ± 0.33 |
| Left amygdala (cc) b | 1.84 ± 0.23 | 2.04 ± 0.32 | 1.92 ± 0.20 | 2.06 ± 0.30 |
a
Marijuana users > Controls, p<0.05;
b
Males > Females, p<0.05