Fig. 2. Sequence profile uncovering short-patch repair. (A) A partial sequence of ARG4 amplified from a single recombinant. The arrows point to sequence differences between the parental alleles, which are indicated underneath. Red arrows correspond to sites where the two parental bases are superimposed indicating an absence of MMR and uncovering a mixed clone. Green arrows indicate sites where only one of the parental bases is found. (B and C) The sequence of two subclones derived from the initial mixed clone.