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. Author manuscript; available in PMC: 2011 Jul 19.
Published in final edited form as: Hum Genet. 2006 Oct 7;120(6):837–845. doi: 10.1007/s00439-006-0242-x

Fig. 2.

Fig. 2

FISH analysis using the RP11-138C22 probe to confirm an atypical 22q11.2 deletion. Fluoresence in situ hybridization (FISH) validation of the RP11-138C22 probe to detect atypical 22q11DS deletions. A control individual (a) showing two copies of chromosome 22q11 using the RP11-138C22 probe. Individuals 1 (b) and 23 (c) are negative by FISH analysis for the TUPLE1 probe but are positive for the deletion using the RP11-138C22 probe due to the extent of their deletion, which was confirmed by qPCR analysis (Fig. 1)