Table 1. HDV replication is inhibited by application of interferons alpha or gamma.

	% HDV replication in presence of inhibitor
Time when inhibitor present (hours)	PreS1 peptide	IFN-alpha	IFN-gamma
−1 to +3	9±6	19±5	20±12
−1 to +16	4±2	8±2	15±10
+3 to +16	9±6	17±8	38±21
+16 to +80	65±36	37±17	40±23

Times of addition of inhibitors are measured relative to 3-h of virus exposure. The preS1 peptide was present at 50 nM while the interferons were at 600 U/ml. All assays were performed in at least triplicate, and the data expressed relative to control hepatocytes that were not treated with inhibitors. The indicated standard error of the mean includes the errors in both the control and the treated cultures.