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Baseline levels of cytokines predict response to aflibercept. A, elevated levels of CTACK/CCL27, MCP3/CCL7, MIF, IP-10/CXCL10, and CA9 predict response to aflibercept. Box-whisker plots: horizontal line in the middle portion of the box, mean. Bottom and top boundaries of boxes, 25th and 75th percentiles, respectively. Lower and upper whiskers, 5th and 95th percentiles, respectively. B, odds ratio and 95% confidence intervals for individual chemokines.
