Figure 3.
Meta-analysis comparing pharmacologic interventions with placebo. The abbreviations “Sib,” “Orl,” and “Rim” refer to sibutramine, orlistat, and rimonabant, respectively. The dosage of rimonabant (mg/d) also is shown. A positive standardized mean difference (SMD) indicates a greater reduction in symptoms of depression with pharmacotherapy. The size of individual study markers is proportional to the weight of that study in the analysis. The midpoint of the diamond marker represents the overall SMD, and the width of the diamond corresponds to the 95% CI.