Table 1.
Baseline patient characteristics and selected clinical data of patients (n=1022)
| Microvesicular Steatosis | |||
|---|---|---|---|
| Present (n=102) | Absent (n=920) | p-value® | |
| Age at enrollment (yrs) | 50.2 ±12.5 | 49.5 ± 11.9 | 0.4 |
| Females (%) | 66 | 63 | 0.6 |
| Caucasians (%) | 88 | 84 | 0.5 |
| BMI (kg/m2)€ | 36.1 ± 7.6 | 34.4 ±6.4 | 0.1 |
| Diabetes (%) | 24.5 | 29.5 | 0.3 |
| HOMA–IR† | 4.4 (3.4–5.9) | 4.0 (2.6–6.3) | 0.3 |
| AST (U/L)* | 50 (36–71) | 45 (32–65) | 0.07 |
| ALT (U/L)* | 63 (46–102) | 65 (43–97) | 0.6 |
Values with age, gender, race, and BMI are expressed as mean with standard deviation.
HOMA-IR: Homeostatic model assessment for Insulin resistance, only non-diabetic patients with insulin and glucose measurements within 6 months of liver biopsy were included (n=505).
IQR- median interquartile ranges of AST and ALT values obtained within 6 months of liver biopsy (n=650).
Only patients with height and weight measurements within 6 months of the liver biopsy were included (n=636).
P-values derived from chi-square tests (gender, diabetes), Fisher’s Exact Test (race), and Wilcoxon rank sum test for continuous variables.