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. Author manuscript; available in PMC: 2012 May 2.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Nov 2;0(1):10.1002/ajmg.b.31136. doi: 10.1002/ajmg.b.31136

Table III.

Significant Associations for Theta ERO from Case-Control GWAS and Family-Based Replication

Stage I: GWAS
 Stage II: Replication
SNP Gene Minor Allele MAF Effect Size (β ± SE)a P-Value MAF Effect Size (β ± SE)a P-Value Combined P-Valueb
rs4907240 ARID5A A 0.227 0.254 ± 0.055 3.93 × 10−6 0.259 0.104 ± 0.055 5.75 × 10−2 3.68 × 10−6
rs13831 GNAS1 T 0.240 −0.209 ± 0.052 6.47 × 10−5 0.250 −0.147 ± 0.053 5.95 × 10−3 6.07 × 10−6
rs2294015 ANXA13 G 0.334 0.211 ± 0.048 1.05 × 10−5 0.379 0.092 ± 0.048 5.84 × 10−2 9.39 × 10−6
rs7916403 HTR7 T 0.492 0.096 ± 0.045 3.20 × 10−2 0.474 0.167 ± 0.047 3.88 × 10−4 1.53 × 10−4
a

Genetic effect in the direction of minor allele.

b

Unadjusted P-values obtained from Fisher’s combined probability test [Fisher, 1925].