Table 1.

Distinct strategies to target the subpopulations of the striatum.

	Classical transgenesis or knock-in	BAC	Other
D1R striatonigral neurons	NSE-tTA (Chen et al., 1998)	drd1a-EGFP, Chrm4-EGFP (Gong et al., 2003)	Volkensin toxin (Harrison et al., 1990)
	drd1a-tox176 (Drago et al., 1998)	drd1a-tdTomato (Shuen et al., 2008)	PPTA-tTA AAV (Hikida et al., 2010)
	drd1a-Cre (Heusner et al., 2008)	drd1a-Cre (YAC) (Mantamadiotis et al., 2002)	pDyn-hM4D HSV (Ferguson et al., 2011)
		drd1a-Cre (EY262 line) (Gong et al., 2007)
		drd1a-DARPP-32/Flag (Bateup et al., 2008)
		drd1a-EGFP-L10A (Heiman et al., 2008)
		drd1a-iRNA (mGluR5 knock-down) (Novak et al., 2010)
D2R striatopallidal neurons	drd2-hIL-2Rα (Sano et al., 2003)	drd2-EGFP (Gong et al., 2003)	OX7-saporin toxin (Roberts et al., 1993)
		drd2-Cre (ER44 line) (Gong et al., 2007)	PPE-tTA AAV (Hikida et al., 2010)
		drd2-DARPP-32/Myc (Bateup et al., 2008)	pEnk-hM4D HSV (Ferguson et al., 2011)
		drd2-EGFP-L10a (Heiman et al., 2008)
		adora2a-Cre (Durieux et al., 2009)
ChAT interneurons	mGluR2-hIL-2Rα (Kaneko et al., 2000)	Chat-EGFP (Gong et al., 2003) Chat-Cre (GM24 and GM60) (Gong et al., 2007)	AF64A toxin (Mantione et al., 1981) SP-PE35 toxin (Saka et al., 2002)
NPY-NO interneurons	n/a	Npy-Cre (DeFalco et al., 2001)	SP-PE35 toxin (Saka et al., 2002)
		Npy-Tau-Sapphire-GFP (Pinto et al., 2004; Roseberry et al., 2004)
		Npy-hrGFP (van den Pol et al., 2009)
		Nos1-EGFP, Npy-Cre (RH26-CRE and RH28-CRE) (http://www.gensat.org)
PV-interneurons	Pvalb-IRES-Cre (Hippenmeyer et al., 2005) Pvalb-2A-Cre (Madisen et al., 2009)	Pvalb-EGFP (Meyer et al., 2002) Pvalb-EGFP (Gong et al., 2003) Pvalb-Cre (Tanahira et al., 2009)	n/a
CR interneurons	n/a	n/a	n/a

n/a: not available.