Table 3.
Differences of brain activity between patients with Parkinson’s disease and normal subjects in performing in-phase movements
Brain region | Coordinates |
t-value | Cluster size | ||
---|---|---|---|---|---|
x | y | z | |||
Normal–Parkinson’s disease | |||||
Left thalamus | −2 | −8 | −3 | 9.17 | 182 |
SMA-proper | 2 | −8 | 62 | 9.09 | 84 |
Left putamen | −20 | −2 | 17 | 8.71 | 59 |
Right thalamus | 18 | −16 | −2 | 8.37 | 87 |
Right globus pallidus | 16 | −8 | −4 | 8.09 | 57 |
Parkinson’s disease–normal | |||||
Left post-central gyrus | −42 | −22 | 32 | 10.29 | 511 |
Left superior parietal lobule | −28 | −50 | 56 | 9.07 | 221 |
Right cerebellum, posterior lobe, tonsil | 30 | −42 | −32 | 8.69 | 40 |
Right precuneus | 24 | −48 | 48 | 8.64 | 65 |
Right post-central gyrus | 53 | −21 | 53 | 8.41 | 24 |
Right SM1 | 14 | −26 | 66 | 8.25 | 54 |
Right cerebellum, posterior lobe, tonsil | 16 | −54 | −34 | 8.21 | 31 |
Left premotor cortex | −18 | −9 | 54 | 8.21 | 34 |
Right cerebellum, anterior lobe, culmen | 2 | −36 | −23 | 8.10 | 22 |
Left cerebellum, posterior lobe, tonsil | −36 | −50 | −38 | 8.06 | 33 |
List of the brain regions showing significantly more activity in normal subjects than in patients with Parkinson’s disease (Normal–Parkinson’s disease), or more activity in patients with Parkinson’s disease than in normal subjects (Parkinson’s disease–Normal), in performing in-phase movements (two sample t-test, P < 0.05, corrected). The coordinates are given as stereotaxic coordinates referring to the atlas of Talairach and Tournoux (1988).