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. 2010 Jun 20;133(8):2394–2409. doi: 10.1093/brain/awq151

Table 3.

Differences of brain activity between patients with Parkinson’s disease and normal subjects in performing in-phase movements

Brain region Coordinates
t-value Cluster size
x y z
Normal–Parkinson’s disease
 Left thalamus −2 −8 −3 9.17 182
 SMA-proper 2 −8 62 9.09 84
 Left putamen −20 −2 17 8.71 59
 Right thalamus 18 −16 −2 8.37 87
 Right globus pallidus 16 −8 −4 8.09 57
Parkinson’s disease–normal
 Left post-central gyrus −42 −22 32 10.29 511
 Left superior parietal lobule −28 −50 56 9.07 221
 Right cerebellum, posterior lobe, tonsil 30 −42 −32 8.69 40
 Right precuneus 24 −48 48 8.64 65
 Right post-central gyrus 53 −21 53 8.41 24
 Right SM1 14 −26 66 8.25 54
 Right cerebellum, posterior lobe, tonsil 16 −54 −34 8.21 31
 Left premotor cortex −18 −9 54 8.21 34
 Right cerebellum, anterior lobe, culmen 2 −36 −23 8.10 22
 Left cerebellum, posterior lobe, tonsil −36 −50 −38 8.06 33

List of the brain regions showing significantly more activity in normal subjects than in patients with Parkinson’s disease (Normal–Parkinson’s disease), or more activity in patients with Parkinson’s disease than in normal subjects (Parkinson’s disease–Normal), in performing in-phase movements (two sample t-test, P < 0.05, corrected). The coordinates are given as stereotaxic coordinates referring to the atlas of Talairach and Tournoux (1988).