Table 5. Cox proportional hazards models of mortality and number of preventative therapies used among PAD subjects without recognized CVD.
Model 1 | Model 2 | Model 3 | |||||
---|---|---|---|---|---|---|---|
N | HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p | |
No preventative therapies* | 244 | ref | ref | ref | |||
One preventative therapy | 129 | 1.12 (0.6-2.1) | 0.7 | 1.15 (0.6-2.2) | 0.7 | 1.24 (0.6-2.5) | 0.5 |
Multiple preventative therapies (≥ 2) | 77 | 0.79 (0.4-1.7) | 0.5 | 0.63 (0.2-1.7) | 0.3 | 0.35 (0.2-0.86) | 0.02 |
Therapies include statin, anti-platelet therapy, and/or ACEI/ARB.
Model 1 = Adjusted for age, gender, race/ethnicity
Model 2 = Model 1 + atherosclerotic risk factors (diabetes, hypertension, hyperlipidemia, smoking, and chronic kidney disease)
Model 3 = Model 2 + health insurance status, education level, and socioeconomic status (based on poverty-income ratio)