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Increased mRNA (cohort 1) and protein expression (cohort 2) of MCM3, Chk1, and Chk2 are associated with an impaired survival. Kaplan-Meier analysis of RFS and OS according to (A) MCM3, (B) CHK1, and (C) CHK2 mRNA levels in cohort 1. Kaplan-Meier analysis of OS according to immunohistochemical (A) MCM3, (B) Chk1, and (C) Chk2 staining in cohort 2.
