Table 1.

Associations between Chk1, Chk2, and MCM3 and Patient and Tumor Characteristics in Cohorts 1 and 2.

Cohort	1			2
Variable	CHK1	CHK2	MCM3	Chk1	Chk2	MCM3
Age
R	0.102	0.069	0.168	-0.009	0.038	0.126
P	.1	.265	.006	.914	.652	.139
n	263	263	263	141	145	140
Differentiation grade
R	0.329	0.186	0.323	0.328	0.270	0.286
P	<.001	.003	<.001	<.001	.001	.001
n	263	260	260	141	145	140
Clinical stage
R	0.13	0.108	0.141	0.129	0.116	0.181
P	.035	.080	.022	.141	.185	.04
n	263	263	263	131	133	130
RBM3
R	-0.247	-0.192	-0.253	0.126	0.074	0.074
P	<.001	.002	<.001	.138	.38	.386
n	263	263	263	140	143	140
CHK1/Chk1
R		0.440	0.599		0.451	0.462
P		<.001	<.001		<.001	<.001
n		263	263		139	137
CHK2/Chk2
R	0.440		0.412	0.451		0.509
P	<.001		<.001	<.001		<.001
n	263		263	139		139

n indicates number of tumor samples; R, Spearman correlations coefficient.

P < .005 in bold.