TABLE 1.
Demographics, drug use, and psychiatric diagnoses of the participants recorded after randomization at intake (means ± SD)
| Variables | Citicolinea | Placebo |
|---|---|---|
| Demographics | ||
| Number of subjects | 15 | 14 |
| Raceb | 1/0/1/11/2 | 0/1/0/13/0 |
| Age | 38.4 ± 4.5 | 39.0 ± 5.3 |
| Weight (lbs) | 188.2 ± 32.5* | 154.9 ± 20.3 |
| Sex (Male/Female) | 11/4 | 7/7 |
| Years of Education | 12.6 ± 1.3 | 12.0 ± 1.6 |
| Age began regular use of cocaine | 22.9 ± 5.4 | 24.7 ± 7.7 |
| Years of regular use of cocaine | 15.5 ± 6.1 | 14.3 ± 6.6 |
| Drug use | ||
| Smoked cocaine (instances per week) | 3.4 ± 1.9c | 4.1 ± 1.9 |
| Snort (intranasal) cocaine (instances per week) | 2.8 ± 0.7d | 1.8 ± 1.1e |
| Alcoholic beverages (drinks per week) | 12.0 ± 14.2 | 15.2 ± 21.3 |
| Marihuana cigarettes (per week) | 4.0 ± 2.8f | 3.9 ± 3.5f |
| Tobacco cigarettes (per day) | 8.5 ± 7.3g | 9.1 ± 4.9g |
| Psychiatric diagnoses | ||
| Cocaine dependence | 15 | 14 |
| Alcohol abuse or dependence | 7 | 9 |
| Marihuana abuse or dependence | 6 | 7 |
| Substance abuse induced-mood disorder | 1 | 2 |
a
1,000 mg/day, p.o
b
Hispanic/American Indian/Cape Verdian/African-American/Caucasian
c
13 out of 15 study participants
d
6 out of 15 study participants
e
2 out of 14 study participants
f
6 study participants in each group
g
11 study participants in each group
*
p<0.05 (t test for independent samples)