Table 2.
Adverse events occurring in more than 10 cycles.
| Event | Grade 1–4-related events (N) | |||
|---|---|---|---|---|
| 1 | 2 | 3 | 4 | |
| Nonhaematological | ||||
| Alopecia | 7 | 12 | NA | NA |
| Anorexia | 6 | 6 | 0 | 0 |
| Asthenia | 1 | 16 | 4 | 0 |
| Canalicular enzymes | 34 | 5 | 2 | 0 |
| Constipation | 5 | 16 | 1 | 0 |
| Dermatitis | 9 | 5 | 0 | 0 |
| Diarrhea | 7 | 1 | 3 | 0 |
| Dysgeusia | 8 | 5 | 0 | 0 |
| Haematuria | 12 | 2 | 2 | 0 |
| Hypobicarbonatemia | 13 | 0 | 0 | 0 |
| Mucositis | 17 | 12 | 3 | 0 |
| Nausea | 23 | 15 | 3 | 0 |
| Transaminitis | 18 | 3 | 1 | 0 |
| Vomiting | 20 | 8 | 6 | 0 |
|
| ||||
| Hematological | ||||
| Anemia | 41 | 20 | 5 | 0 |
| Thrombocytopenia | 7 | 3 | 2 | 0 |
| Febrile Neutropenia | NA | NA | 5 | 1 |
NA: not applicable.