Table 1.
Not in coma after arrest (n = 51 arrests, 42 patients) | In coma after arrest, not cooled (n = 18 arrests, 17 patients) | In coma after arrest, cooling started (n = 11 arrests, 11 patients) | Statistical test for significance | |
---|---|---|---|---|
Sex | ||||
Male | 40 (95) | 17 (100) | 10 (91) | P = 0.53e |
Age, in yrs | 70.4 ± 11.1 | 72.4 ± 12.4 | 69.5 ± 13.0 | F = 0.24, P = 0.79f |
In-hospital Arrest | 47 (92) | 16 (94) | 11 (100) | |
Initial cardiac rhythm | ||||
PEA/asystole | 47 (92) | 18 (100) | 10 (91) | P = 0.51e |
VTach/VFib | 4 (8) | 0 (0) | 1 (9) | |
ROSC in minutes | 5.2 ± 4.6 range (0.1–20)a | 33.5 ± 21.2 range (5–60)b | 21.9 ± 11.9 range (5–35)c | F = 29.6, P < 0.001f |
Mechanism of arrest | ||||
1° Cardiac | 24 (47) | 4 (22) | 2 (18) | P = 0.07e |
1° Pulmonary | 13 (25) | 8 (44) | 3 (27) | P = 0.33e |
1° Gastrointestinal | 1 (2) | 2 (11) | 1 (9) | P = 0.18e |
Sepsis/infection | 5 (10) | 2 (11) | 0 (0) | P = 0.72e |
Intraoperative | 2 (4) | 2 (11) | 0 (0) | P = 0.30e |
Unknown/other | 6 (12) | 0 (0) | 5 (45) | P = 0.005 |
Comorbidities | ||||
CAD or CHF | 24 (57) | 9 (53) | 7 (64) | P = 0.83e |
Vascular RFs | 26 (62) | 13 (76) | 6 (55) | P = 0.47e |
Cancer | 8 (19) | 5 (29) | 3 (27) | P = 0.66e |
Pulmonary disease | 8 (19) | 3 (18) | 1 (9) | P = 0.91e |
GI/liver | 5 (12) | 2 (12) | 1 (9) | P = 1.0e |
ESRD | 6 (14) | 3 (18) | 0 (0) | P = 0.41e |
HIV, hepatitis | 3 (7) | 1 (6) | 0 (0) | P = 1.0e |
Substance abused | 3 (7) | 1 (6) | 2 (18) | P = 0.48e |
Expired before discharge | 13 (31) | 16 (94) | 6 (55) | P < 0.001e |
CPC at discharge | ||||
Favorable (1-2) | 27 (64) | 1 (6) | 5 (45) | P < 0.001e |
Unfavorable (3–5) | 15 (36) | 16 (94) | 6 (55) | |
CPC at 6 Months | ||||
Favorable (1-2) | 19 (45) | 0 (0) | 3 (27) | P = 0.001e |
Unfavorable (3–5) | 23 (55) | 17 (100) | 8 (73) |
Values as whole number and (percentage), except in case of continuous variable, given as mean ± standard deviation.
ROSC: return of spontaneous circulation; 1°: primary; VTach, ventricular tachycardia; VFib: ventricular fibrillation; vascular RFs: cardiovascular risk factors.
Values as whole number and (percentage), except in case of continuous variable, given as mean ± standard deviation.
aData available for 34 of 51 arrests; bavailable for 10 of 18 arrests; cavailable for 8 of 11 arrests; dsubstance abuse includes alcohol abuse; eFisher's exact test; fanalysis of variance (ANOVA).