Table I. Amino acid substitutions encoded by the rpoB gene in rifR clones.
| Mutation | Amino acid substitution (No. of mutants) |
|---|---|
| GC→AT | S512F (32), D516N (47), S522F (7), H526Y (82), R529H (4), S531F (34), P564L (30), S574F (7) |
| GC→TA | S509R*(1), S512Y*(25), Q513K*(10), D516Y (34), S522Y*(2), H526N*(24), H526Q (5), R529S (1), R529L (2), S531Y (19), G534C*(4), G534V*(4), G534S*(2), G570C*(4), S574Y*(7) |
| GC→CG | S522C*(1), H526D*(7), A532P*(1), G534R*(1), I572M*(1) |
| AT→GC | L511P*(8), S512P (33), Q513R (4), D516G*(177), N518D*(4), L533P (8), I572T*(1) |
| AT→CG | S509R*(2), L511R*(2), Q513P (14), T563P (6), I572L*(27), I572S*(9) |
| AT→TA | Q513L (20), D516V (10), H526L*(13), L533H*(1), I572F (27) |
*Substitutions that are not previously reported.