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Doxorubicin decreases viability in WT cardiomyocytes in a time and dose-dependent manner. Doxorubicin 1, 10 and 50 µM was administered to neonatal cardiomyocytes obtained from WT mice. Viability was assessed at 6 and 24 h by MTT assay. At 6 h viability was decreased only at 50 µM, whereas at 24 h viability was decreased at both 1 and 10 µM and severely decreased at 50 µM. * P < 0.05 vs. baseline.
