Fig. 3.

Schematic representations of hagfish (upper panel) and lamprey (lower panel) gVLR genes and their rearranged forms (mVLRs). Coding regions are color-coded (gray—5′ UTR; orange—signal peptide; blue—LRRNT; yellow—LRRCT, pink—C terminus). Solid red lines indicate introns that disrupt the 5′ UTR, while black double dotted lines indicate the intervening sequence. LRR1, LRR, and CP are imported into the mature VLR from flanking regions (not shown) and supplant the intervening sequence during the rearrangement process.