Table 3.

Genotype and allele frequencies of TNFα (G-308A) polymorphism in RA patients and matched controls.

Genotype/allele	RA (N = 106)		Control (N = 126)		P-value	RR	EF*/PF
	N	%	N	%
GG	68	64.15	63	50	0.033♣	1.79	0.261*
GA	35	33.01	48	38.09	0.492	0.66	0.156
AA	3	2.83	15	11.90	0.012♣	0.25	0.337
GA and AA	38	35.84	63	50	0.033♣	0.55	0.223
G-allele	171	80.66	174	69.04	0.005♣	1.87	0.242*
A-allele	41	19.33	78	30.95	0.005♣	0.48	0.242

Note: N, number of subjects;

^♣Statistically significant.

Abbreviations: EF, etiological fraction; PF, preventive fraction.