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. 2008 Jun;9(2):167–178. doi: 10.1089/ham.2007.1066

Table 3.

Adjusted Mean Values ± SE by ACE Genotype from ANCOVA for Various Physiologic Measures

 
 Adjusted mean values ± SE
  
  
  
  
  I/I (n = 72) I/D (n = 52) D/D (n = 14) S CovariatesaBP NAAP p-value, ACE effect
HVR, L/min−1/%−1 0.71 ± 0.05 0.67 ± 0.06 0.55 ± 0.13       0.456
Inline graphic, L/min−1 2.08 ± 0.04 2.04 ± 0.04 2.06 ± 0.08 x x x 0.673
Inline graphic, L/min−1/kg−1 35.3 ± 0.6 34.9 ± 0.8 36.0 ± 1.5 x x x 0.663
Inline graphic @ max, % 82.7 ± 0.5 82.0 ± 0.6 80.0 ± 1.1 x x   0.071
a

Covariates are S = sex, BP = birthplace, and NAAP = Native American ancestry proportion. A covariate was retained in ANCOVA when it had an independent effect on an outcome variable (P ≤ 0.05), or as indicated in the text.

ACE, angiotensin-converting enzyme; I, insertion; D, deletion; HVR = hypoxic-ventilatory response.